The series is about an orphan boy named Eric Needles, who with his best friend Trevor Troublemeyer and his two female friends, Vana Glama and Kitty Ko, are training to become sidekicks at the Academy for Aspiring Sidekicks in the city of Splittsboro. While dealing with intense sidekick training, Eric must also contend with his strict guardian Maxum Brain, his cruel teacher Professor Pamplemoose, the evil Master XOX and keeping secret the disappearance of his superhero mentor Maxum Man from the city.