This cartoon is based on the popular Marvel comic by Stan Lee and features several of the characters that made it such a success: Cyclops, Jean Grey, Beast, Archangel, Iceman, Wolverine, Gambit, Rogue, Jubilee, and even Bishop, all students of the benevolent Professor X.
Naturally, the people of Earth are scared of mutants, who have superhuman powers ranging from flight and super strength to telepathy and psychokinesis. Ghastly measures, taken out of fear to prevent mutants from seizing power, ironically lead to the eventual rise of villainous mutants who would stop at nothing to rule the world. However, the Professor and his band of X-Men, knowing that the true secret to longevity of the human/mutant relationship is acceptance and harmony, thanklessly lay their lives on the line again and again to thwart the plans of the wicked and save the day as well as their own hides.
While most of the characters and plots from the show originate within the pages of the comic books (Magneto, the Sentinels, Apocalypse, etc.), some (like Morph) were derived solely for the series, giving it a truly original spin all while staying true to its fans.