San Francisco free lance photographer Samantha 'Sam' Russell (Pam Dawber) seems to have her life in order until her teenage sister, Patti(Rebecca Schaeffer), decides to move in and turn Sam's life on it's head. Along with next door neighbor and former beau Jack Kincaid(David Naughton), Sam's agent J.D. Lucas(Joel Brooks), and friend and co-worker Dixie Randazzo(Jenny O'Hara), Sam's life is certainly never boring. Always full of love and laughs along the way, Sam and Patti's life adventures strengthen the bond that only sisters can understand.