Based on the children's books of the same name. A young city girl named Emily Elizabeth is able to adopt a neighbor's puppy as a birthday gift. In the end she chooses the runt of the litter, a small red dog she names Clifford. Despite nobody expecting him to grow, Emily's love soon makes Clifford grow to over 25 feet tall! With Clifford too big for the city, the family moves to the open space of Birdwell Island. Each episode teaches life lessons in two 15-minute stories with the first focusing on Clifford and his animal friends, especially bulldog T-Bone and purple poodle Cleo, and the second focusing on Emily and her human friends. John Ritter provided Clifford's voice.