An American-Japanese animated fantasy-comedy television series from Cartoon Network and TV Tokyo, produced by Renegade Animation and Cartoon Network Studios in Japan. The show was created by Sam Register, who also serves as the series' executive producer.
According to Register, the target audience of the show is boys and girls from six to eleven years old. However, the show also has a following of fans of the real-life Ami Onuki and Yumi Yoshimura who make up the Japanese pop duo PUFFY, known as "Puffy AmiYumi" in North America. Register, a fan of the band, wished to spread its fame to other parts of the world and thus produced the cartoon.