The_Phantom
Planescape Torment (my favorite game of all time actually)
Baldur's Gate 1 & 2
Star Craft
Daggerfall
Morrowind
Knights of the Old Republic
The Sims 2
Julie Saves the Eagles
The Magic School Bus Explores the Ocean**
YM Digital Makeover Magic
JumpStart Spy Masters: Unmask the Prankster*
Teen Digital Diva
Secret Paths to Your Dreams CD-ROM
Your Notebook with Help from Amelia CD-ROM
Sabrina the Teenage Witch: Brat Attack***
Rockett's New School
everGirl
The American Girls Premiere
The Starfire Soccer Challenge
Barbie Magic Hairstyler
*Sort of a edutainment Spy vs. Spy clone which places pre teen secret agents against the awful masked prankster
**I have the Macintosh port of this PC game
***Possibly a point and click CD-ROM adventure game featuring the voice of Melissa Joan Hart as Sabrina the Teenage Witch (the entire game was created using Macromedia Director)