Ok, I may have found it for myself now and it does have Lea Thompson in it.
A Will of Their Own
Miniseries examining the changing role of women in America as seen through the eyes of three generations of one family. In 1894, 19-year-old immigrant Annie Jermaine sails from Europe to become the housemaid for a wealthy American doctor. Later, Annie shatters social taboos when she marries the doctor's son and trains as a nurse, but she is never allowed to use her medical knowledge because of the belief that patients won't trust a woman. The saga follows Annie's descendants as they struggle with prejudices against the women of their time: daughter Amanda is a rebellious photo journalist who lives a bohemian lifestyle; granddaughter Sarah, raised as a debutante, later becomes the lonely wife of a powerful U.S. Senator; and great-granddaughter Susan grows up as a hippie and becomes a doctor, opening a health clinic for battered women.
1998