Most of them are funny or offensive, in fact back in the day my friends and I would play a game called "Laugh or Slap". The idea being that you would walk up to a girl in a bar or wherever, and use a really lame and or offensive pick up line, if the girl laughed you bought her a drink, and your friends would refund you, if she slapped you, then they would buy you a drink. Some are generic, as they tend to get around, but here were some of my faves. Mind you, I never actually thought any of these were smooth, the idea was to get slapped, or laughed at.
Are you Irish? Because my penis is Dublin (doublin' for those who don't get it)
Are those space pants you're wearing? Because your ass is out of this world.
Nice Shoes. Let's fuck. (that's an old standard, I'm sure you've heard it)
Anybody have some others? I do, but I don't believe in them, it was just for a game. If I were actually interested in a lady I wouldn't say any of that stupid shit.