A prequel series to the Clifford series from 2000. Set two years (1998) before the events of Clifford the Big Red Dog, the series focuses on when Clifford is a tiny red puppy, the runt of the litter in a litter of puppies given birth to by the pet dog of Emily Elizabeth's neighbor, Mr. Bradley (who appeared in an episode of the first cartoon series, "Little Clifford") and after he had been adopted by Emily Elizabeth and before he grew up into a giant red adult dog, forcing the Howards to move to Birdwell Island so Clifford would have plenty of room, the series shows Clifford and Emily Elizabeth's life and friends before they moved from New York City to Birdwell Island and all of their adventures to make room.