The anime adaptation of the first game premiered on April 4, 2009[16] and was produced by Aniplex's A-1 Pictures.[17][18] The series was directed by Yasutaka Yamamoto[19] and written by Michiko Yokote under the Project Valkyria Group.[19] Valkyria Chronicles was aired on Animax, Tokyo MX, MBS, CBC, Chiba TV, Television Kanagawa, Television Hokkaido, BS11 and TVQ Kyushu Broadcasting.[20] Generally following the storyline of the original game, the anime version differs from its source in terms of characterization of main players such as Alicia, and introduces a character unique to the anime, Ramal Valt. While retaining elements of the CANVAS Engine's look, the characters were redesigned for the anime by Atsuko Watanabe.

The original score for the anime is composed and conducted by the game's composer Hitoshi Sakimoto and performed by the Czech Film Orchestra. The first opening theme song, "Asu e no Kizuna"[21] was performed by Animax Anison Grand Prix winner Catherine St. Onge, under her chosen moniker of Himeka.[22][23][24] A CD single of the song was released on May 27, 2009.[25] The first ending theme, "Ano Kaze ni Notte" (アノ風ニノッテ, "Riding on that Wind") was sung by the band Pe'zmoku with a CD single released on May 27, 2009 in a regular and special edition.[25][26] Maria performed the series's second opening theme, "Kanashimi Rensa" (カナシミレンサ, "Chain of Sorrow"),[27] which was used from the 14th episode on.[28] The second ending song, "Hitotsu no Negai" (ひとつの願い, "A Single Wish"), was sung by Hikari Inoue[28] beginning from Episode 14 until Episode 25. Episode 26's ending song was "Brightest Morning", also performed by Hikari Inoue. CD singles for "Kanashimi Rensa" and "Hitotsu no Negai" were released on August 12, 2009 and August 5, 2009.[28]

Region 2 DVDs of all 26 episodes were released across nine volumes, beginning on August 5, 2009,[29] and concluding on April 7, 2010.[30]Valkyria Chronicles III was adapted into a two-episode original video animation series