JoJo's Bizarre Adventure: Phantom Blood (ジョジョの奇妙な冒険 ファントムブラッド JoJo no Kimyō na Bōken Fantomu Buraddo) is a 2007 Japanese anime film based on Part 1 of the JoJo's Bizarre Adventure manga series entitled Phantom Blood. The film was released on February 17, 2007, to commemorate JoJo author Hirohiko Araki's 20th year of publishing. Animation was handled by Studio A.P.P.P., the same staff who handled the earlier JoJo's Bizarre Adventure OVA based on Part 3 Stardust Crusaders. The film had a limited screening in Japanese theaters and has never been released on home video.

The film generally follows the story of the Phantom Blood manga arc, featuring Jonathan Joestar in his fight against adoptive brother Dio Brando, who after years of attempting to break Jonathan (including kissing his childhood love Erina Pendleton) poisons their father and becomes an immortal vampire through the use of a Stone Mask. Jonathan receives training in an ancient martial arts technique known as Hamon from the eccentric Italian man Will A. Zeppeli, whose father originally discovered the Stone Mask, and the two attempt to kill Dio before he uses his newfound powers to enslave humanity.

Shueisha terminated their relationship with studio A.P.P.P. until later reboot in 2012.