The first anime adaptation animated by Shaft aired in Japan between January and March 2009. A second anime season, Maria†Holic: Alive, premiered on April 8, 2011. Both seasons of the anime series have been licensed by Sentai Filmworks.revolves around a high school girl named Kanako Miyamae, who is scared of boys and breaks out in hives if a boy touches her. During her second year of high school, she enrolls in an all-girls school hoping to find a female romantic partner. However, her ideal candidate, Mariya Shidō, turns out to be a sadistic cross-dressing boy.Kanako Miyamae (宮前 かなこ Miyamae Kanako)
Voiced by: Asami Sanada (Japanese); Jessica Calvello (English)
Kanako is the protagonist of the story. She is a second year high school transfer student to Ame no Kisaki, a Catholic-based all-girls academy. Kanako has an inherent fear of men which began in elementary school when a piece of her recorder and P.E. uniform were stolen. When coming into physical contact with any man, she instantaneously breaks out in hives. This has significantly contributed to her fear of boys. Kanako is almost solely interested in girls in regards to her ideal romantic relationships. She instantly and constantly suffers from nosebleeds—a visible indication of sexual perverseness frequently used in anime and manga. Her reason for transferring to Ame no Kisaki is to look for her one true love. Kanako begins her reflections on her situation with the phrase "Dear mother in heaven." Kanako is also quite tall (standing at 175 cm or 5'9"), making her height (and her weight) emotional weak spots. She also takes constant verbal abuse from Mariya and his maid, Matsurika. She is often called a 'pervert', or 'lesbian', or other nicknames they happen to give her.
Mariya Shidō (祇堂 鞠也 Shidō Mariya)
Voiced by: Yū Kobayashi (Japanese); Monica Rial (English)
Mariya is a cross-dressing boy who attends Ame no Kisaki as a girl as a means to win the chairmanship of both the all-male and all-female schools where hi