Time and time again, Cobra has been on the threshhold of global domination, only to be thwarted by the Joes. But a new force comes to Cobra with a plan. Cobra-La wants to steal the Joes' Broadcast Energy Transmitter in order to ripen plant pods that have been launched into the earth's outter atmosphere. The spores within these plants will contain enough spores to eliminate mankind turning them into mindless beasts. Cobra Commander had been originally sent by Golobulus, Cobra-La's leader, to destroy mankind after they fell during the ice age. The Joes capture Serpentor, but in a huge battle Duke is knocked into a coma. During tha attack on Cobra-La the Joes were captured, so it's up to the trainees and Pro WWF wrestler Sargeant Slaughter to rescue the Joes, stop Cobra-La, and save the world.