The Szalinski family once again discovers size really does matter in this follow-up to Honey, I Shrunk the Kids and Honey, I Blew up the Kid. Inventor Wayne Szalinski (Rick Moranis) is preparing to donate his problematic shrinking/expanding machine to the Smithsonian Institution as he and his wife, Diane (Eve Gordon), get ready for a long weekend away from their son, Adam (Bug Hall). Wayne's brother, Gordon (Stuart Pankin), his wife, Patty (Robin Bartlett), daughter, Jenny (Allison Mack), and son, Mitch (Jake Richardson), volunteer to look after Adam while Wayne and Diane are away, but as luck would have it (and the title would lead you to expect), all four grown-ups are accidentally zapped by Wayne's shrinking ray. As the kids run amok, their miniaturized parents must contend with monstrously huge insects, wrinkles in the carpet that look like canyons, and other threats to the existence of the suddenly tiny.