A vampire hunter, named Jack Crow, team is slaughtered by a vampire known as the master vampire, Valek. Jack now must find a relic known as the Berziers Cross before Valek does. If Valek finds this relic, it will allow vampires the ability to survive daylight with nothing in their in way to stop them.

    The film was followed by two sequels: Vampires: Los Muertos (produced by John Carpenter and directed by Tommy Lee Wallace) and Vampires: The Turning.